MedicalToday

Description

In healthy individuals, glutamine is a neutral, nonessential amino acid. Amino acids are critical to humans, since they form the proteins that are the building blocks for many body tissues, including muscles. Glutamine is the most abundant amino acid in our bodies. It performs several important functions in the body, particularly in those that are stressed because of certain diseases or conditions. Glutamine can be added to the body medically by physicians or through dietary supplements that people purchase without prescriptions.

Pharmacology.

Leflunomide’s active metabolite (M1) inhibits dihydro-oratate dehydrogenase, thereby inhibiting pyrimidine biosynthesis. M1 exhibits immunomodulating and anti-inflammatory effects.

Administration and Adult Dosage.

PO for rheumatoid arthritis 100 mg/day for 3 days, then 20 mg/day. Reduce dose to 10 mg if 20 mg is not tolerated.

Pediatric Dosage.

Safety and efficacy not established.

Geriatric Dosage.

Same as adult dosage.

Dosage Forms.

Description

Pyridoxine, or vitamin B6, is a member of the water soluble family of B vitamins. It is necessary in the processes to metabolize proteins, fats, and carbohydrates, to make hormones and neurotransmitters, and to support the immune system. It also plays a role in the production of normal, healthy red blood cells and some of the neurotransmitters needed for proper nervous system function. In conjunction with folic acid and cobalamin, it acts to reduce homocysteine levels, thus lowering the risk of developing heart disease.

Pharmacology.

Infliximab is a chimeric monoclonal antibody that binds to soluble and transmembrane forms of TNF a, thereby neutralizing the activity of TNFa and inhibiting TNFa binding to its receptor sites. It has no effect on lymphotoxin (TNFa).Infliximab induces pro-inflammatory cytokines including interleukins 1 and 6 and increases endothelial cell permeability by enhancing leukocyte migration.

Administration and Adult Dosage.

Description

Psyllium is a seed used for medicinal purposes taken from the common fleawort, Plantago psyllium. There are about 250 species of the genus Plantago found worldwide; they belong to the Plantaginaceae family. The most common species producing seed for medicinal use, in addition to P. psyllium, are P. afra, P. isphagula, P. ovata, and P. indica.