Glutathione

Description

Glutathione is produced in the human liver and plays a key role in intermediary metabolism, immune response and health, though many of its mechanisms and much of its behavior await further medical understanding. It is also known as gamma-Glutamyl-cysteine-glycine and GHS. It is a small protein composed of three amino acids, cysteine, glutamic acid and glyceine. Glutatione is found in two forms, a monomer that is a single molecule of the protein, and a dimmer that is two of the single molecules joined together. The monomer is sometimes called reduced glutathione, while the dimmer is also called oxidized glutathione. The monomer is the active form of glutathione. Oxidized glutathione is broken down to the single molecule by an enzyme called glutathione reductase.

Breast reconstruction

Definition

Breast reconstruction is a series of surgical procedures performed to recreate a breast. Reconstructions are commonly begun after portions of one or both breasts are removed as a treatment for breast cancer. A breast may need to be refashioned for other reasons such as trauma or to correct abnormalities that occur during breast development.

Purpose

Wide local excision

Definition

Wide local excision is a type of surgery for breast cancer. It is considered “breast-conserving” surgery because only the malignant tumor and a surrounding margin of normal breast tissue are removed. Lymph nodes in the armpit (axilla) may also be removed. This procedure is also called lymph node dissection.

Purpose

Modified radical mastectomy

Definition

A surgical procedure that removes the breast, surrounding tissue, and nearby lymph nodes that are affected by cancer.

Purpose

Breast reduction

Definition

Breast reduction is a surgical procedure performed to decrease the size of the breasts.

Purpose

Women with very large breasts (macromastia, or mammary hyperplasia) seek breast reduction for relief of back, shoulder, and neck pain. They may also feel uncomfortable about their breast size and have difficulty finding clothing that will fit properly. Additionally, breast reduction may be needed after reconstructive surgery following the surgical removal of cancerous breast tissue (mastectomy), to make the breasts more symmetric.

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