Hepatitis | Medical Today

LEFLUNOMIDE (Arava)

Pharmacology.

Leflunomide’s active metabolite (M1) inhibits dihydro-oratate dehydrogenase, thereby inhibiting pyrimidine biosynthesis. M1 exhibits immunomodulating and anti-inflammatory effects.

Administration and Adult Dosage.

PO for rheumatoid arthritis 100 mg/day for 3 days, then 20 mg/day. Reduce dose to 10 mg if 20 mg is not tolerated.

Pediatric Dosage.

Safety and efficacy not established.

Geriatric Dosage.

Same as adult dosage.

Dosage Forms.

In corneal transplant, also known as keratoplasty, a patient’s damaged cornea is replaced by the cornea from the eye of a human cadaver. This is the most common type of human transplant surgery and has the highest success rate. Eye banks acquire and store eyes from donors to supply the need for transplant corneas.

Purpose

Written by Medical Today in: Health Information | Tags: Alterations, antibiotic, antibiotics, Astigmatism, bacteria, body, Bones, Bulge, Bulges, burn, Burns, Cataract Surgery, Cataracts, Cells, Chemical Burns, Chemicals, Cornea, Corneal Transplant, Corneal Transplantation, Corneal Transplants, Corneas, Corrective Lenses, Deficiencies, disease, Extremities, eye, Eye Banks, Feelings, Fuchs Dystrophy, glasses, glaucoma, growth, heart, hepatitis, Herpes Virus, hospital, Httpv, Human Cadaver, Incision, Incisions, infection, infections, Inflammation, injuries, injury, Irritability, Irritant, Irritants, kidney, Kidneys, laser, lead, Mechanical Trauma, Mechanisms, medication, Mso, Natural Curvature, Nerve Endings, Nerves, Normals, Ophthalmologist, Ophthalmologists, Organs, pain, Prescriber, Prevention, Procedure Description, Protein, Proteins, Protozoa, Pterygium, Remedy, ring, rings, Scars, screening, Severity, skin, Stevens Johnson Syndrome, suffering, surgery, symptoms, Tissues, Transparent Layer, Trauma, treatment, Viable Options, vision, Wounds

SUMATRIPTAN SUCCINATE (Imitrex)

Pharmacology.

Sumatriptan is a serotonin (5-HT) analogue and a selective agonist at 5-HT1D receptors in cerebral vascular smooth muscle. Receptor activation results in migraine relief by vasoconstriction of intracranial blood vessels and attenuation of the release of vasoactive peptides responsible for inflammation of sensory nerves.

Administration and Adult Dosage.

Written by Medical Today in: Drug Information | Tags: abortion, acid, Adult Dosage, Agonist, Attenuation, Bioavailability, Bioavailable, breathing, Breaths, burn, Burns, Caffeine, cardiac, chest, Dehydration, diabetes, Discontinuation, disease, Dizziness, dosage, drug, drugs, Dyspnea, Efficacy, eye, Feces, food, Headache, headaches, heart, hepatitis, High Blood Pressure, Hr Period, hypertension, Imitrex, Inflammation, Initial Dose, Ischemia, kidney, Kidney Disease, Kidneys, Lesions, liver, Metabolism, Metabolites, Mg Dose, migraine, Migraine Attack, migraines, Mso, muscle, muscles, Nasal Spray, neck, Nerves, Normals, Nostril, Numbness, Oral, pain, Patient Instructions, Pharmacokinetics, Pharmacology, pregnancy, pregnant, Prevention, Protein, Proteins, Receptor Activation, Receptors, Sensory Nerves, Severity, skin, SSRI, Succinate, Sumatriptan, Tightness In Chest, Tissues, treatment, Vascular Smooth Muscle, Vasoactive Peptides, Vasoconstriction

LIVER LET LIVE

Wake up and smell the coffee

According to a study in the Journal of the National Cancer Institute, drinking one to two cups of the black stuff halves your risk of liver cancer. UK research also found medium-roasted coffee has higher antioxidant activity than dark-roasted.

Learn from lager lovers

Milk thistle capsules, loaded with silymarin, help patch up liver damage.

Know how to take a jab

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LEFLUNOMIDE (Arava)

Corneal transplantation

SUMATRIPTAN SUCCINATE (Imitrex)

LIVER LET LIVE

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